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SARS-CoV-2,whichcausestheglobalpandemiccoronavirusdisease2019(Covid-19),belongstoafamilyofvirusesknownascoronaviruses.TheSARS-CoV-2Sproteinisaglycoproteinthatmediatesmembranefusionandviralentry.TheRBDofSARS-CoV-2bindsametallopeptidase,angiotensin-convertingenzyme2(ACE-2).SeveralemergingSARS-CoV-2genomeshavebeenidentifiedincludingtheOmicron,orB.1.1.529,variant.FirstidentifiedinNovember2021inSouthAfrica,theOmicronvariantquicklybecamethepredominantSARS-CoV-2variantandisconsideredavariantofconcern(VOC).TheOmicronvariantcontains15mutationsinRBDdomainthatpotentiallyaffectviralfitnessandtransmissibility.ThemajorityofthemutationsareinvolvedinACE-2bindingandOmicronbindsACE-2withgreateraffinity,potentiallyexplainingitsincreasedtransmissibility.Severalofthesemutationsarealsoidentifiedinfacilitatingimmuneescapeandreducingneutralizationactivitytoseveralmonoclonalantibodies.CX3CL1用作粘附分子,而两种形式都是表达CX3CR1的靶细胞的化学吸引力。Recombinant Mouse TFPI-2 Protein,hFc Tag

Recombinant Mouse TFPI-2 Protein,hFc Tag,标准物质

Recombinant Biotinylated Human AFP (HLA-A*02:03) Protein,His-Avi Tag性能参数表达区间及表达系统(Source)RecombinantBiotinylatedHumanAFP(HLA-A*02:03)ProteinisexpressedfromHEK293withHistagandAvitagattheC-terminal..ItcontainsGly25-Thr305(HLA-A*02:03),Ile21-Met119(B2M)andFMNKFIYEIpeptide.[Accession|AAA03604.1(HLA-A*02:03)&P61769(B2M)&FMNKFIYEI]分子量大小(MolecularWeight)TheproteinhasapredictedMWof50.70kDa.Duetoglycosylation,theproteinmigratesto53-60kDabasedonTris-BisPAGEresult.(Endotoxin)Lessthan1EUperμgbytheLALmethod.纯度(Purity)>95%asdeterminedby>95%asdeterminedbyHPLC制剂(Formulation)Lyophilizedfrom0.22μmfilteredsolutioninPBS(pH7.4).Normally8%trehaloseisaddedasprotectantbeforelyophilization.重构方法(Reconstitution)Centrifugetubesbeforeopening.Reconstitutingtoaconcentrationmorethan100μg/mlisrecommended.Dissolvethelyophilizedproteinindistilledwater.Recombinant Human CTACK/CCL27UbcH7耗尽导致S期延长和增殖速率降低,提示它可能在细胞周期中起作用。

Recombinant Mouse TFPI-2 Protein,hFc Tag,标准物质

Recombinant Human ACE2/ACEH Protein,hFc Tag性能参数,分子别名(Synonyms)ACE2;ACEH;ACE-2表达区间及表达系统(Source)HumanACE2/ACEHProteinisexpressedfromHEK293withhFctagattheC-Terminus.ItcontainsGln18-Ser740.[Accession|Q9BYF1-1]分子量大小(MolecularWeight)TheproteinhasapredictedMWof109.2kDa.Duetoglycosylation,theproteinmigratesto115-130kDabasedonSDS-PAGEresult.Endotoxin)Lessthan1EUperμgbytheLALmethod.纯度(Purity)>95%asdeterminedbySDS-PAGEandHPLC.活性(Activity)ELISAData:ImmobilizedSARS-COV-2SpikeS(B.1.1.529/Omicron)Trimer,HisTagat1μg/ml(100μl/well)ontheplate.DoseresponsecurveforHumanACE2,hFcTagwiththeEC50of13.7ng/mldeterminedbyELISA.制剂(Formulation)Lyophilizedfrom0.22μmfilteredsolutioninPBS(pH7.4).Normally8%trehaloseisaddedasprotectantbeforelyophilization.重构方法(Reconstitution)Centrifugethetubebeforeopening.Reconstitutingtoaconcentrationmorethan100μg/mlisrecommended.Dissolvethelyophilizedproteinindistilledwater.

Recombinant Biotinylated Human MSLN/Mesothelin Protein,hFc-Avi Tag分子别名(Synonyms)Mesothelin;CAK1;MSLN;MPFSMRP表达区间及表达系统(Source)BiotinylatedHumanMSLN/MesothelinProteinisexpressedfromHEK293withhFctagandAvitagattheC-Terminus.ItcontainsGlu296-Gly580.[Accession|Q13421-2]分子量大小(MolecularWeight)TheproteinhasapredictedMWof61.1kDa.Duetoglycosylation,theproteinmigratesto70-80kDabasedonSDS-PAGEresult.(Endotoxin)Lessthan1EUperμgbytheLALmethod.纯度(Purity)>95%asdeterminedbySDS-PAGEandHPLC.活性(Activity)ELISAData:ImmobilizedAnti-MSLNAntibody,hFcTagat1μg/ml(100μl/well)ontheplate.DoseresponsecurveforBiotinylatedHumanMSLN,hFcTagwiththeEC50of18.4ng/mldeterminedbyELISA.eotaxin-2在空肠和脾脏中组成型表达, 它也可以通过过敏原挑战和IL-4在肺中诱导。

Recombinant Mouse TFPI-2 Protein,hFc Tag,标准物质

3C蛋白酶是切割小RNA病毒科非结构蛋白的关键酶,在病毒复制过程中发挥着重要作用。鼻病毒属于小RNA病毒科,其中的人鼻病毒3C蛋白酶基因编码区全长552bp,编码的蛋白质相对分子质量约为22000Da。人鼻病毒3C蛋白酶具有高度的酶切特异性,能特异切割位于Gln-Gly之间的肽键,识别位点为Leu-Glu-Val-Leu-Phe-Gln↓Gly-Pro。本公司将人鼻病毒3C蛋白酶的编码区基因,在大肠杆菌中进行重组表达,纯化后获得了高纯度的重组3C蛋白酶,该蛋白酶能特异切割含有3C酶切位点的融合蛋白,具有良好的生物学活性。同时,本公司生产的3C蛋白酶带有GST和MAT标签蛋白,有利于后期将其从酶切体系中去除。产品性质:中文别名(Chinesesynonym):3C蛋白酶英文别名(Englishsynonym):3CProtease来源(Source):大肠杆菌表达标签(label):GST-3CProtease-MAT纯度(Purity):经SDS-PAGE及HPLC分析,纯度>95%分子量(Molecularweight):47.38kDa比活性(Specificactivity):500U/ml缓冲液组分(Buffer):50mMTris-HCl,150mMNaCl,1mMEDTA,1mMDTT,pH7.0酶活定义(UnitDefinition):在缓冲液中切割100μg被检测的融合蛋白,反应条件为4℃16小时,切割率≥90%运输和保存方法:干冰运输;保存于-20℃。OSM与白血病抑制因子(LIF)密切相关,实际上,除了其在人类中的特定受体外,它实际上还使用了LIF受体。Recombinant Human IL-27RA/TCCR Protein,hFc Tag

LAG-1与MIP-1β(ACT II同种型)相同,Lag-1趋化吸引力单核细胞,并表现出活性作为HIV抑制因子。Recombinant Mouse TFPI-2 Protein,hFc Tag

Name:AITRL,MouseSynonyms:Activation-inducedTNFRmemberLigand,TNFSF18,GITRL,TL-6Description:Activation-InducibleTNF-RelatedLigand(AITRL),alsoknownasGlucocorticoid-InducedTNF-RelatedLigand(GITRL),belongstothetumornecrosisfactorsuperfamily(TNFSF).AITRLisaTypeIIsingletransmembraneproteinandshareslowconservationwithintheextracellulardomainwithotherTNFSFmembers.AITRLisexpressedonmacrophages,immatureandmaturedendriticcellsandBcells.Itsreceptor,Activation-InducibleTNFRfamilyReceptor(AITR),isexpressedonTlymphocytes,naturalkiller(NK)cells,andantigen-presentingcells.AfterbindingbyAITRL,AITRcanbereleased.AITRactivationincreasesresistancetotumorsandviralinfectionsandisinvolvedinautoimmuneandinflammatoryprocesses.Inaddition,activatedAITRincreasesTCR-inducedTcellproliferationandcytokineproductionandrescuesTcellsandNKcellsfromapoptosis.RecombinantmouseActivation-InducibleTNF-RelatedLigand(rmAITRL)producedinE.Recombinant Mouse TFPI-2 Protein,hFc Tag

浦斯瑞(上海)生物医药有限公司是一家有着先进的发展理念,先进的管理经验,在发展过程中不断完善自己,要求自己,不断创新,时刻准备着迎接更多挑战的活力公司,在江苏省等地区的化工中汇聚了大量的人脉以及**,在业界也收获了很多良好的评价,这些都源自于自身的努力和大家共同进步的结果,这些评价对我们而言是比较好的前进动力,也促使我们在以后的道路上保持奋发图强、一往无前的进取创新精神,努力把公司发展战略推向一个新高度,在全体员工共同努力之下,全力拼搏将共同浦斯瑞(上海)生物医药供应和您一起携手走向更好的未来,创造更有价值的产品,我们将以更好的状态,更认真的态度,更饱满的精力去创造,去拼搏,去努力,让我们一起更好更快的成长!

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Recombinant Human CD5L Protein 2024-06-28

RecombinantBiotinylatedHumanOX40/TNFRSF4/CD134Protein(PrimaryAmineLabeling),hFcTag性能参数分子别名(Synonyms)OX40Lreceptor;CD134;TNFRSF4;Ly-70表达区间及表达系统(Source)BiotinylatedHumanOX40/TNFRSF4/CD134Protein(PrimaryAmineLabeling)isexpressedfromHEK293withhFctagattheC-Terminus.ItcontainsLeu29-Ala216.[Accession|P4348...

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